A Review of Artemisia annua L.: Its Genetics, Biochemical Characteristics, and Anti-Malarial Efficacy
نویسنده
چکیده
This paper presents a review on the genetics of A. annua as an important plant species for the treatment of malaria. A short history on the discovery of the plant is discussed. Furthermore, a clear description of the characteristics of A. annua is presented as the plant’s chemistry, mechanism of action and efficacy are thoroughly discussed. Many cytogenetic studies on A. annua focusing on the production of the antimalarial drug, artemisinin are also presented. New technologies on artemisinin production are also discussed focusing on the use of microorganisms. The last part of the review discusses issues and future prospects of A. annua and artemisinin production for malaria therapy.
منابع مشابه
A Systematic Review of Anti-malarial Properties, Immunosuppressive Properties, Anti-inflammatory Properties, and Anti-cancer Properties of Artemisia Annua
Artemisia annua belongs to the asteraceae family, indigenous to the mild climate of Asia. The aim of this study was to overview its anti-malarial properties, immunosuppressive properties, anti-inflammatory properties and anti-cancer properties. This systematic review was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases. The initial search strategy ide...
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The complete chloroplast genome of Artemisia annua (Asteraceae), the primary source of artemisinin, was sequenced and analyzed. The A. annua cp genome is 150,995 bp, and harbors a pair of inverted repeat regions (IRa and IRb), of 24,850 bp each that separate large (LSC, 82,988 bp) and small (SSC, 18,267 bp) single-copy regions. Our annotation revealed that the A. annua cp genome contains 113 ge...
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